Azithromycin is indicated for the treatment of the following infections of mild to moderate severity: Lower respiratory tract infections: bronchitis 、pneumonia. Uncomplicated skin and skin structure infections. Acute otitis media. Upper respiratory tract infections: acute sinusitis、tonsillitis and acute streptococcal pharyngitis(Note: Penicillin is the usual drug of choice in the treatment of Streptococcus pyogenes pharyngitis, including the prophylaxis of rheumatic fever. Azithromycin appears to be almost as effective in the treatment of streptococcal pharyngitis. However, substantial data establishing the efficacy of azithromycin in the subsequent prevention of rheumatic fever are not available at present.)