Clarithromycin is indicated for treatment of infections caused by susceptible organisms. Such infections include: Upper respiratory tract infections. Lower respiratory tract infections. Skin and soft tissue infections. Disseminated or localized mycobacterial infections due to Mycobacterium avium or Mycobacterium intracellulare. Localized infections due to Mycobacterium chelonae, Mycobacterium fortuitum, or Mycobacterium kansasii. Prevention of disseminated Mycobacterium avium complex infection in HIV-infected patients with CD4 lymphocyte counts less than or equal to 100/mm3. Duodenal ulcer. Clarithromycin in the presence of acid supression is indicated for the treatment of duodenal ulcer and in reducing the rate of ulcer recurrance.